Author

Thư Ngọc-Anh Trịnh

University of St AndrewsORCID 0009-0008-9179-9925Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alison L. DicksoniD· 1 shared Carlin J. Hamill· 1 shared Clarissa Melo CzeksteriD· 1 shared David James HarrisoniD· 1 shared Greice Michele ZickuhriD· 1 shared Ramasubramanian SundaramoorthyiD· 1 shared Sally L. ShirraniD· 1 shared Silvia Synowksy· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Alison L. DicksonORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJul 31, 2026

Dimerization and Threonine-Dependent Stabilization Govern Human YRDC Catalysis

Thư Ngọc-Anh Trịnh, Greice Michele Zickuhr, Alison L. Dickson…·Clarissa Melo Czekster

This study elucidates the mechanism of YRDC catalysis, showing that threonine stabilizes the enzyme and dimerization is critical for function, with disease-linked mutations disrupting these processes.

DOI 10.64898/2025.12.03.692196

humanproteomics

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