Cancer BiologybioRxivPreprint
CMTM6-Silencing Microbial Immunotherapy Reprograms PDAC Tumors and Restores T-cell Function
Chiswili Yves Chabu, Robert A. Kazmierczak, M Hasani…·Bolni Marius Nagalo
This paper develops iSTORM, a Salmonella-based immunotherapy that silences CMTM6 in PDAC tumors, enhancing T-cell function and tumor control while maintaining safety.
DOI 10.64898/2026.01.26.701790