Author

Caroline Jan

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Martine Guillermier· 2 shared A. Chekroun· 1 shared Alexandre CharletiD· 1 shared Ana Carolina da SilvaiD· 1 shared Ana Rita FernandesiD· 1 shared Aude PanatieriD· 1 shared Audrey Fayard· 1 shared Aurélie Amadio· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersNeuroscience

Martine Guillermier

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Acetylcholine drives astrocytic JAK2-STAT3 signaling to modulate male-to-female approach behavior

Tom Lakomy, Camille Falconnier, Kai‐Yi Wang, Tony Barbay, Valentin Grelot, Sydney Barthelemot, Martine Guillermier, A. Chekroun, Caroline Jan, Elisa Degl’Innocenti, María-Angeles Carrillo-de Sauvage, Rémi Bos, Alexandre Charlet, Carole Escartin, Lucile Ben Haim

The paper shows that acetylcholine activates astrocytic JAK2-STAT3 signaling in male mice, which is necessary for context-appropriate approach behavior toward estrus females.

bioRxiv · Sep 8, 2026 · PreprintNeuroscience

L-serine diet restores impaired adult neurogenesis in the hippocampus of 3xTg-AD mice

Emmanuel Than‐Trong, Lucille Torres, Mylène Gaudin, Caroline Jan, Aurélie Ghettas, Aurélie Amadio, The Brainbank Neuro-CEB Neuropathology Network, Stéphane H. R. Oliet, Aude Panatier, Gilles Bonvento

This study shows that a L-serine-enriched diet improves adult neurogenesis in 3xTg-AD mice without affecting amyloidosis.

bioRxiv · Apr 29, 2026 · PreprintNeuroscience

AAV-mediated allele-specific silencing alleviates neuropathology in a novel non-human primate model of Spinocerebellar ataxia type 3

Carina Henriques, Diana Duarte Lobo, Ana Carolina da Silva, Ana Rita Fernandes, Miguel Monteiro Lopes, Audrey Fayard, Caroline Jan, Sophie Lecourtois, Martine Guillermier, Julien Flament, João Castelhano, Miguel S. Castelo-Branco, Rui Caetano Oliveira, Philippe Hantraye, Padmaja Yalamanchili, , Rui Jorge Nobre

This study evaluates AAV9-miR-ATXN3 in a non-human primate model of SCA3, showing reduced neuropathology through allele-specific silencing of mutant ATXN3.

bioRxiv · Oct 2, 2025 · PreprintMolecular Biology