PTEN Regulates Myofibroblast Activation in Valvular Interstitial Cells based on Subcellular Localization
Dilara Batan, Georgios Tseropoulos, Bruce E. Kirkpatrick, Carrie Bishop, Kaustav Bera, Alex Khang, Mary C. M. Weiser-Evans, Kristi S. Anseth
This study shows PTEN suppresses myofibroblast activation in valvular interstitial cells by promoting quiescence and reducing stiffness-induced activation.
Advanced Biology · Apr 14, 2025Peer-reviewedCell Biology