Kaustav Bera

This study shows that nuclear mechanics influence intestinal stem cell differentiation by sensing tissue shape and modulating lamin-A levels.

This study shows that a synthetic hydrogel enables crypt formation in intestinal organoids without exogenous laminin, revealing insights into mechanical and matricellular signaling.

This study shows PTEN suppresses myofibroblast activation in valvular interstitial cells by promoting quiescence and reducing stiffness-induced activation.

The paper develops mathematical descriptors to quantify fibroblast phenotypes and validates them using drug-treated cells to predict myofibroblast activation.

This study uses bottlebrush polymer hydrogels to show how strain-stiffening affects hMSC protrusion formation and mechanosensing.