Cancer BiologybioRxivPreprint
Klf4-dependent pivotal role of smooth muscle-derived Gli1+ lineage progenitor cells in lung cancer progression
Sizhao Lu, Andre Navarro, Amber M. Johnson…·Mary C. M. Weiser-Evans
This study identifies AdvSca1-SM cells as a key component of lung tumors and shows that Klf4-dependent regulation of these cells affects cancer progression and immunotherapy response.
DOI 10.1101/2025.05.30.657094