A Novel Liver Cancer-Selective Histone Deacetylase Inhibitor Is Effective Against Hepatocellular Carcinoma and Induces Durable Responses with Immunotherapy
Bocheng Wu, Subhasish Tapadar, Zhiping Ruan, Carrie Qi Sun, Rebecca S. Arnold, Alexis Johnston, Jeremiah Olorunjuwon Olugbami, Uche Okuu Arunsi, David A. Gaul, John A. Petros, Tatsuya Kobayashi, Dan Gabriel Duda, Adegboyega K. Oyelere
This paper identifies a novel HDAC inhibitor, STR-V-53, that effectively targets HCC and enhances immunotherapy responses in mouse models.
ACS Pharmacology & Translational Science · Sep 5, 2024Peer-reviewedCancer Biology