Dual-acting Estrogen Receptor Modulator-Histone Lysine Demethylase Inhibitors
Dipak T. Walunj, Jeremiah Olorunjuwon Olugbami, Bocheng Wu…·Adegboyega K. Oyelere
This paper develops dual-acting inhibitors combining estrogen receptor ligands with KDM inhibitors, showing potent anti-proliferative effects against both ER+ and ER- breast cancer cells in xenograft models.