Gene-by-environmental modulation of longevity and weight gain in the murine BXD family
Suheeta Roy, Maroun S. Bou Sleiman, Pooja Jha, Jesse F. Ingels, Casey J. Chapman, Melinda S. McCarty, Jesse Dylan Ziebarth, Michael Hook, Anna Sun, Wenyuan Zhao, Jinsong Huang, Sarah M. Neuner, Lynda A. Wilmott, Thomas M. Shapaker, Arthur G. Centeno, , Robert W. Williams
The paper examines how diet and genetics interact to affect longevity and weight gain in mice, finding that genetic differences significantly influence the impact of high-fat diets on lifespan.
Nature Metabolism · Sep 22, 2021Peer-reviewedGenetics