Jesse F. Ingels

Multi-Omic Profiling of the Liver Across Diets and Age in a Diverse Mouse Population

The paper uses multi-omics data from mice to identify gene-environment-age interactions and causal molecular networks linked to longevity.

Gene-by-environmental modulation of longevity and weight gain in the murine BXD family

The paper examines how diet and genetics interact to affect longevity and weight gain in mice, finding that genetic differences significantly influence the impact of high-fat diets on lifespan.

Respiratory Syncytial Virus Infections Induce Hypermetabolism in Pediatric Upper Airways

This study shows RSV infection increases metabolism in pediatric upper airway cells and fluids, suggesting hypermetabolism as a potential therapeutic target.

Computational approaches towards reducing contamination in single-cell RNA-seq data

The paper presents two computational methods to reduce contamination in single-cell RNA-seq data, improving clustering and biological interpretation.

The expanded BXD family of mice: A cohort for experimental systems genetics and precision medicine

BXD mouse family doubled to 150 inbred strains segregating over 6 million variants, with roughly 10,000 located recombinations and a public phenome exceeding 7000 traits.

Identification of a functional non-coding variant in the GABAA receptor α2 subunit of the C57BL/6J mouse reference genome: Major implications for neuroscience research

The paper identifies a functional non-coding variant in the GABRA2 gene of the C57BL/6J mouse strain, showing its impact on Gabra2 expression and implications for neuroscience research.