Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle
Sarah Amandine Caroline Voisin, Kirsten Seale, Macsue Jacques, Shanie Landen, Nicholas R. Harvey, Larisa Margaret Haupt, Lyn Robyn Griffiths, Kevin J. Ashton, Vernon G. Coffey, Jamie‐Lee M. Thompson, Thomas M. Doering, Maléne E. Lindholm, Colum P. Walsh, Gareth W. Davison, Rachelle E Irwin, , Nir Eynon
This study shows exercise training reduces epigenetic and transcriptomic aging in human skeletal muscle, while muscle disuse accelerates transcriptomic aging.
Aging Cell · May 2, 2023Peer-reviewedMolecular Biology