Author

Catherine Paradis‐Bleau

Université de Montréal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:E. coli· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Fardin GhobakhlouiD· 2 shared Felipe CavaiD· 1 shared Imène Kouidmi· 1 shared Larbi Mokhtari· 1 shared Laura ÁlvareziD· 1 shared Tom A. PfeiferiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

Fardin GhobakhlouORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintApr 9, 2025

High-throughput LacZ/CPRG screen identifies novel potential antibiotics targeting Gram-negative bacterial envelopes to combat resistance

Fardin Ghobakhlou, Larbi Mokhtari, Tom A. Pfeifer, Catherine Paradis‐Bleau

This study identifies 57 compounds, including three non-antibiotics, that disrupt Gram-negative bacterial envelopes using a LacZ/CPRG reporter assay, with alexidine showing the strongest activity.

2 citations

E. colimouse

𝕏 PostBluesky

MicrobiologybioRxivPreprintApr 10, 2024

Phenotypic and Transcriptomic Characterization of ElyC-Defective Escherichia coli Cells Reveal the Importance of ElyC in Cell Envelope Biology at Optimal and Sub-Optimal Temperatures

Fardin Ghobakhlou, Imène Kouidmi, Laura Álvarez…·Catherine Paradis‐Bleau

This study shows ElyC is essential for cell envelope integrity and PG biosynthesis at 21°C but has a moderate role at 37°C, affecting morphology, antibiotic resistance, and stress response pathways.

DOI 10.1101/2024.04.10.588480

E. colibulk RNA-seq

𝕏 PostBluesky