Author

Fardin Ghobakhlou

National Institutes of HealthORCID 0000-0002-1391-2012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Alan G. HinnebuschiD· 1 shared Catherine Paradis‐Bleau· 1 shared Hongen ZhangiD· 1 shared Larbi Mokhtari· 1 shared Swati GaikwadiD· 1 shared Tom A. PfeiferiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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1 shared paperGenetics

Alan G. HinnebuschORCID

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2 papers

Recent·Most cited

High-throughput LacZ/CPRG screen identifies novel potential antibiotics targeting Gram-negative bacterial envelopes to combat resistance

Fardin Ghobakhlou, Larbi Mokhtari, Tom A. Pfeifer, Catherine Paradis‐Bleau

This study identifies 57 compounds, including three non-antibiotics, that disrupt Gram-negative bacterial envelopes using a LacZ/CPRG reporter assay, with alexidine showing the strongest activity.

bioRxiv · Apr 9, 2025 · PreprintMicrobiology

Yeast eIF2A has a minimal role in translation initiation and uORF-mediated translational control in vivo

Swati Gaikwad, Fardin Ghobakhlou, Hongen Zhang, Alan G. Hinnebusch

This study investigates the role of eIF2A in yeast translation, finding minimal impact on translational efficiency and uORF-mediated control in vivo.

bioRxiv · Oct 6, 2023 · PreprintGenetics