Author

Tom A. Pfeifer

University of British ColumbiaORCID 0000-0001-8252-6687Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Catherine Paradis‐Bleau· 1 shared Fardin GhobakhlouiD· 1 shared Larbi Mokhtari· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperMicrobiology

Catherine Paradis‐Bleau

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintApr 9, 2025

High-throughput LacZ/CPRG screen identifies novel potential antibiotics targeting Gram-negative bacterial envelopes to combat resistance

Fardin Ghobakhlou, Larbi Mokhtari, Tom A. Pfeifer, Catherine Paradis‐Bleau

This study identifies 57 compounds, including three non-antibiotics, that disrupt Gram-negative bacterial envelopes using a LacZ/CPRG reporter assay, with alexidine showing the strongest activity.

2 citations

E. colimouse

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