MEDUSA: Maintaining Entire DNA Duplexes for Utmost Sequencing Accuracy
Kan Xiong, Rachel Li, Ning Li, Ruolin Liu, Azeet Narayan, Justin Rhoades, Catherine Song, Robert Coleman Lindsley, Heather Anne Parsons, Gerassimos Mike Makrigiorgos, Viktor A. Adalsteinsson
MEDUSA improves sequencing accuracy by minimizing DNA duplex resynthesis during library preparation, achieving lower residual SNV frequency in genomic and cell-free DNA.
Clinical Chemistry · Apr 23, 2026Peer-reviewedGenomics