Author

Rachel Li

Broad InstituteORCID 0000-0002-8112-4237Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Rachel Li1 paper · University of South Dakota;

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Azeet NarayaniD· 2 shared Gerassimos Mike MakrigiorgosiD· 2 shared Kan XiongiD· 2 shared Ruolin LiuiD· 2 shared Viktor A. AdalsteinssoniD· 2 shared Catherine Song· 1 shared Farzaneh DarbeheshtiiD· 1 shared Hayet Radia ZeggariD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenomics

Azeet NarayanORCID

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2 papers

Recent·Most cited

MEDUSA: Maintaining Entire DNA Duplexes for Utmost Sequencing Accuracy

Kan Xiong, Rachel Li, Ning Li, Ruolin Liu, Azeet Narayan, Justin Rhoades, Catherine Song, Robert Coleman Lindsley, Heather Anne Parsons, Gerassimos Mike Makrigiorgos, Viktor A. Adalsteinsson

MEDUSA improves sequencing accuracy by minimizing DNA duplex resynthesis during library preparation, achieving lower residual SNV frequency in genomic and cell-free DNA.

Clinical Chemistry · Apr 23, 2026Peer-reviewedGenomics

Methyl-CODEC enables simultaneous methylation and duplex sequencing

Ruolin Liu, Farzaneh Darbeheshti, Laurel Walsh, Rachel Li, Jin H. Bae, Hayet Radia Zeggar, Azeet Narayan, Kan Xiong, Gerassimos Mike Makrigiorgos, Viktor A. Adalsteinsson

Methyl-CODEC enables simultaneous methylation and duplex sequencing, improving mutation detection and distinguishing methylated Cs from mutations.

Nucleic Acids Research · May 21, 2025Peer-reviewedGenomics