Selective axonal translation of prenylated Cdc42 mRNA isoform supports axon growth
Seung Joon Lee, Amar N. Kar, Matthew D. Zdradzinski, Priyanka Patel, Pabitra Kumar Sahoo, Riki Kawaguchi, Byron J. Aguilar, Kelsey D. Lantz, Caylee McCain, Giovanni Coppola, Qun Lu, Jeffery L. Twiss
The paper shows that prenyl-Cdc42 mRNA localizes to PNS axons and promotes axon growth through localized translation and prenylation.
Journal of Cell Science · Mar 5, 2021Peer-reviewedNeuroscience