OmpA controls intracellular survival of Acinetobacter baumannii through TFEB activation and lysosomal remodeling
Irene Molina Panadero, Angela Rey Hidalgo, María José López Carballo, Celia Atalaya Rey, Manuel Javier Muñoz, Younes Smani
This study identifies an OmpA-iPLA2-LPC-ORAI1-TFEB signaling axis that enables Acinetobacter baumannii to survive intracellularly by modulating lysosomal function and counteracting host defenses.
bioRxiv · Apr 19, 2026 · PreprintMicrobiology