Accurate bacterial outbreak tracing with Oxford Nanopore sequencing and reduction of methylation-induced errors
Mara Lohde, Gabriel E. Wagner, Johanna Dabernig‐Heinz, Adrian Viehweger, Sascha D. Braun, Stefan Monecke, Celia Diezel, Claudia Stein, Mike Marquet, Ralf Ehricht, Mathias Wilhelm Pletz, Christian Brandt
This study evaluates Oxford Nanopore sequencing for outbreak tracing, identifies methylation-induced errors, and proposes a masking workflow to improve accuracy.
bioRxiv · Sep 15, 2023Molecular Biology