Author

Celina Shen

Salk Institute for Biological Studies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Amanda Cyril· 2 shared Anvita KomarlaiD· 2 shared Christina G. TowersiD· 2 shared Ginevra DoglioniiD· 2 shared Louis R. ParhamiD· 2 shared Payel MondaliD· 2 shared Adelaida Estrada-Cardenas· 1 shared Alexandra Fowler· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Amanda Cyril

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2 papers

Recent·Most cited

Rapid optogenetic blockade of autophagy reveals that nuclear pore complex proteins are robust autophagy substrates

Payel Mondal, Amanda Cyril, Dana Mamriev, Louis R. Parham, Igor H. Wierzbicki, Celina Shen, Ginevra Doglioni, Suzanne Dufrense, Anvita Komarla, David J. Gonzalez, Maximiliano A. D’Angelo, Christina G. Towers

The paper develops an optogenetic tool to rapidly inhibit autophagy and identifies nuclear pore complex proteins as autophagy substrates.

bioRxiv · Jul 7, 2026 · PreprintCell Biology

Leveraging autophagy and pyrimidine metabolism to target pancreatic cancer

Suzanne Dufresne, Ramya S. Kuna, Kristiana Wong, Anvita Komarla, Louis R. Parham, Celina Shen, Payel Mondal, Adelaida Estrada-Cardenas, Angelica E. Rock, Joel Encarnación-Rosado, Amanda Cyril, Ginevra Doglioni, Dhanya R. Panickar, Nicole A. Bakas, Douglas J. Sheffler, , Christina G. Towers

This study identifies metabolic adaptations in pancreatic cancer cells resistant to autophagy inhibitors and shows that targeting pyrimidine salvage can enhance treatment efficacy.

bioRxiv · May 29, 2025 · PreprintCancer Biology