Author

Challen A. Pretorius

Saint Louis University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Anish SuriiD· 1 shared Emily Christie· 1 shared Eric L. Ford· 1 shared Evelyn Needham· 1 shared Javier A. CarreroiD· 1 shared Kirsten Foley· 1 shared Kristin Yeung· 1 shared Natalie YakobianiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Anish SuriORCID

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1 paper

Recent·Most cited

Coordinated IL-2 and TGF-β Signaling Activates Stable Regulatory T Cells and Promotes Immune Tolerance

Nicholas M. Jackson, Javier A. Carrero, Kristin Yeung, Evelyn Needham, Emily Christie, Natalie Yakobian, Challen A. Pretorius, Stella G. Hoft, Kirsten Foley, Eric L. Ford, Simon Low, Ronald D. Seidel III, Anish Suri, Natasha M. Girgis, Steven N. Quayle, Richard J. DiPaolo

This study shows coordinated IL-2 and TGF-β3 signaling expands and activates regulatory T cells, reduces autoimmune responses, and promotes immune tolerance.

bioRxiv · Mar 27, 2026 · PreprintImmunology