Author

Steven N. Quayle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anish SuriiD· 3 shared Simon LowiD· 3 shared Natasha M. Girgis· 2 shared Akil AkhtariD· 1 shared Ashwin JainarayananiD· 1 shared Challen A. Pretorius· 1 shared Emily Christie· 1 shared Eric L. Ford· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

Anish SuriORCID

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Author profile →

3 papers

Recent·Most cited

Synaptic synergy of T cell receptor and interleukin 2 receptor in CD8+ T cells

Jesusa Capera, María Navarro‐Pérez, Ashwin Jainarayanan, Salvatore Valvo, Lina Chen, Panyu Fei, Sarah E. Flannery, Román Fischer, Sašo Čemerski, Simon Low, Steven N. Quayle, Raymond J. Moniz, Anish Suri, Michael Loran Dustin

The paper shows that TCR and IL2 receptor signaling synergize at the immunological synapse of CD8+ T cells, enhancing T-T synapse formation and function.

Nature Communications · Oct 7, 2026Peer-reviewedImmunology

Simultaneous TCR and IL-2 agonism selectively enhances epitope-specific CD8 T cell responses during chronic viral infection

Masao Hashimoto, Mohammad Affan Khan, Akil Akhtar, Javed Naim Agrewala, Gordon James Freeman, Natasha M. Girgis, Yu Zhang, Simon Low, Steven N. Quayle, Anish Suri, Rafi Ahmed

This study shows that targeting IL-2 to antigen-specific CD8 T cells enhances their responses during chronic viral infection while sparing non-targeted populations, and combining this with PD-1 blockade further improves outcomes.

Journal of Virology · Jun 15, 2026Peer-reviewedImmunology

Coordinated IL-2 and TGF-β Signaling Activates Stable Regulatory T Cells and Promotes Immune Tolerance

Nicholas M. Jackson, Javier A. Carrero, Kristin Yeung, Evelyn Needham, Emily Christie, Natalie Yakobian, Challen A. Pretorius, Stella G. Hoft, Kirsten Foley, Eric L. Ford, Simon Low, Ronald D. Seidel III, Anish Suri, Natasha M. Girgis, Steven N. Quayle, Richard J. DiPaolo

This study shows coordinated IL-2 and TGF-β3 signaling expands and activates regulatory T cells, reduces autoimmune responses, and promotes immune tolerance.

bioRxiv · Mar 27, 2026 · PreprintImmunology