HIV-1 infection promotes neuroinflammation and neuron pathogenesis in novel microglia-containing cerebral organoids.
Srinivas D. Narasipura, Janet P. Zayas, Michelle K. Ash, Anjelica F. Reyes, Tanner L. Shull, Stéphanie Gambut, James L. A. Szczerkowski, Charia McKee, Jeffrey R. Schneider, Ramón Lorenzo-Redondo, Lena Al‐Harthi, João I. Mamede
This study develops microglia-containing cerebral organoids (CO-iMs) to model HIV-1 infection and its effects on neuroinflammation and neuronal function.
Journal of Neuroinflammation · Feb 10, 2025Peer-reviewedMicrobiology