Author

Stéphanie Gambut

Rush University Medical CenterORCID 0000-0002-0327-0992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

João I. MamedeiD· 2 shared Adolfo García‐SastreiD· 1 shared Andrew TuckwelliD· 1 shared Anjelica F. Reyes· 1 shared Charia McKee· 1 shared Derrick LauiD· 1 shared Gianguido C. Cianci· 1 shared Heather M. Curry· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

João I. MamedeORCID

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2 papers

Recent·Most cited

HIV-1 infection promotes neuroinflammation and neuron pathogenesis in novel microglia-containing cerebral organoids.

Srinivas D. Narasipura, Janet P. Zayas, Michelle K. Ash, Anjelica F. Reyes, Tanner L. Shull, Stéphanie Gambut, James L. A. Szczerkowski, Charia McKee, Jeffrey R. Schneider, Ramón Lorenzo-Redondo, Lena Al‐Harthi, João I. Mamede

This study develops microglia-containing cerebral organoids (CO-iMs) to model HIV-1 infection and its effects on neuroinflammation and neuronal function.

Journal of Neuroinflammation · Feb 10, 2025Peer-reviewedMicrobiology

Recognition of HIV-1 capsid licenses innate immune response to viral infection

Sunnie M. Yoh, João I. Mamede, Derrick Lau, Narae Ahn, María Teresa Sánchez-Aparicio, Joshua E. Temple, Andrew Tuckwell, Nina V. Fuchs, Gianguido C. Cianci, Laura Riva, Heather M. Curry, Xin Yin, Stéphanie Gambut, Lacy M. Simons, Judd F. Hultquist, , Sumit K. Chanda

The paper identifies a two-factor authentication mechanism used by the innate immune system to detect low-abundance HIV-1 DNA through PQBP1-mediated capsid recognition and cGAS recruitment.

bioRxiv · Jan 10, 2022 · PreprintMolecular Biology