A Standardized Protocol to Investigate Trans-Endothelial Trafficking in Zebrafish: Nano-bio Interactions of PEG-based Nanoparticles in Live Vasculature
Ye‐Wheen Lim, Craig A. Bell, Nicholas L. Fletcher, Nicholas D. Condon, Dewan Taslima Akhter, James A. Rae, Charles Ferguson, Nick Martel, James Humphries, Harriet P. Lo, Yeping Wu, Zachary H. Houston, Anne K. Lagendijk, Thomas Edward Hall, Kristofer J. Thurecht, Robert G. Parton
This paper develops a standardized protocol to assess nanoparticle trans-endothelial trafficking in zebrafish, identifying transport mechanisms for PEG-based nanoparticles.
bioRxiv · Jul 23, 2025 · PreprintCell Biology