Anne K. Lagendijk

This study shows that mural cells are not required for BBB function in developing zebrafish but protect against hemorrhage-induced BBB breakdown in adults.

This study identifies circumferential actomyosin bundles as drivers of endothelial cell deformations that regulate vessel diameter and prevent vascular malformations.

This study shows integrin β1-Talin1 at focal adhesions drive uncontrolled endothelial cell enlargement in CCM vasculature, independent of KLF2/4.

The paper introduces a method to analyze nematic order on tissue surfaces of arbitrary geometry, validated in vitro and in vivo, revealing physical insights through 3D reconstruction from 2D image stacks.

This paper develops a standardized protocol to assess nanoparticle trans-endothelial trafficking in zebrafish, identifying transport mechanisms for PEG-based nanoparticles.

This study uses single-cell transcriptomics to investigate Prox1's role in lymphatic endothelial cell fate specification and differentiation in zebrafish, identifying new transcriptional targets and regulatory mechanisms.

This study identifies a genetic interaction between Pkd1 and Wnt5a in controlling lymphatic vascular morphogenesis in mice, showing mutual suppression of lymphatic defects.

The paper identifies junction-based lamellipodia (JBL) as structures driving endothelial cell movement during vascular remodeling, showing their dependence on F-actin and VE-cadherin.