Cheng Zhao

Divergent Entry, Convergent Trafficking in Defensin-Mediated Adenovirus Infection

This study compares intracellular trafficking of defensin-resistant and canonical adenovirus entry routes, finding they converge on common checkpoints and that defensin effects are determined at the cell surface.

Alpha-defensin binding expands human adenovirus tropism

This paper shows that human adenoviruses can bind to cells via alpha-defensins instead of their usual receptors, expanding their tropism to non-susceptible cells.

Phenotypical Rescue of Bmp15 Deficiency by Mutation of Inhibin α (inha) Provides Novel Clues to How Bmp15 Controls Zebrafish Folliculogenesis

This study shows that bmp15 deficiency in zebrafish causes follicle arrest and sex reversal, which can be rescued by inhibin mutation, revealing interactions between bmp15 and the activin-inhibin system in folliculogenesis.

Using Cell line and Patient samples to improve Drug Response Prediction

The paper compares drug response prediction models using cell lines, patients, and integrated data, finding that integrative models outperform cell line-only models and require fewer patients.