Jessica M. Porter

This paper shows human alpha-defensin 5 inhibits enterovirus A71 by stabilizing its capsid and blocking genome release during infection.

This study shows that the adenosine-rich content of the HIV-1 genome is critical for efficient packaging, as demonstrated by Gag-SRSF5 chimera experiments.

This study identifies how human alpha-defensins neutralize AAV2 and AAV6 by blocking viral entry and nuclear trafficking, revealing a common mechanism for inhibiting non-enveloped viruses.

This paper shows that human adenoviruses can bind to cells via alpha-defensins instead of their usual receptors, expanding their tropism to non-susceptible cells.