The crossover function of MutSγ is activated via Cdc7-dependent stabilization of Msh4
Wei He, H. B. D. Prasada Rao, Shangming Tang, Nikhil R. Bhagwat, Dhananjaya S. Kulkarni, Maria A.W. Chang, Christie Hall, Lepakshi Singh, Xiangyu Chen, Nancy M. Hollingsworth, Petr Ćejka, Neil Hunter
This study shows that MutSγ activation during meiosis depends on Cdc7-mediated phosphorylation of Msh4, stabilizing the complex and enabling crossover formation.
bioRxiv · Aug 27, 2018 · PreprintGenetics