Author

Christine N. Evans

Frederick National Laboratory for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Raj ChariiD· 2 shared Alexander A Gooden· 1 shared Bao Quoc TraniD· 1 shared Caroline FromontiD· 1 shared Charles D. SchwietersiD· 1 shared Hiroshi MatsuoiD· 1 shared Julianna C. KingiD· 1 shared King C. ChaniD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Raj ChariORCID

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2 papers

Recent·Most cited

Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma

Xiuxiu Lu, Venkata R. Sabbasani, Vasty Osei Amponsa, Christine N. Evans, Julianna C. King, Sergey G. Tarasov, Marzena Dyba, Sudipto Das, King C. Chan, Charles D. Schwieters, Sulbha Choudhari, Caroline Fromont, Yongmei Zhao, Bao Quoc Tran, Xiang Chen, , Kylie J. Walters

The paper identifies a chemical scaffold targeting hRpn13, revealing a DEUBAD-lacking isoform upregulated in multiple myeloma and demonstrating its potential as a therapeutic target.

Nature Communications · Dec 16, 2021Peer-reviewedMolecular Biology

dbGuide: A database of functionally validated guide RNAs for genome editing in human and mouse cells

Alexander A Gooden, Christine N. Evans, Timothy P. Sheets, Michelle E. Clapp, Raj Chari

dbGuide compiles over 4000 functionally validated guide RNA sequences for CRISPR/Cas9-based knockout in human and mouse, enabling more reliable guide RNA selection.

Nucleic Acids Research · Sep 22, 2020Peer-reviewedBioinformatics