Author

Sulbha Choudhari

Frederick National Laboratory for Cancer Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:benchmark study· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Bao Quoc TraniD· 2 shared Yongmei ZhaoiD· 2 shared Allison F. Gillaspy· 1 shared Andreas SchereriD· 1 shared Ashley Lyn LeClerc· 1 shared Bin ZhuiD· 1 shared Caroline FromontiD· 1 shared Charles D. SchwietersiD· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Bao Quoc TranORCID

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Author profile →

4 papers

Recent·Most cited

HNRNPH1 destabilizes the G-quadruplex structures formed by G-rich RNA sequences that regulate the alternative splicing of an oncogenic fusion transcript

Tam D. Vo, Tayvia Brownmiller, Katherine L. Hall, Tamara L. Jones, Sulbha Choudhari, Ioannis Grammatikakis, Katelyn R. Ludwig, Natasha J. Caplen

The paper shows HNRNPH1 destabilizes G-quadruplexes in G-rich RNA sequences, affecting alternative splicing of an oncogenic fusion transcript in Ewing sarcomas.

Nucleic Acids Research · May 7, 2022Peer-reviewedMolecular Biology

Structure-guided bifunctional molecules hit a DEUBAD-lacking hRpn13 species upregulated in multiple myeloma

Xiuxiu Lu, Venkata R. Sabbasani, Vasty Osei Amponsa, Christine N. Evans, Julianna C. King, Sergey G. Tarasov, Marzena Dyba, Sudipto Das, King C. Chan, Charles D. Schwieters, Sulbha Choudhari, Caroline Fromont, Yongmei Zhao, Bao Quoc Tran, Xiang Chen, , Kylie J. Walters

The paper identifies a chemical scaffold targeting hRpn13, revealing a DEUBAD-lacking isoform upregulated in multiple myeloma and demonstrating its potential as a therapeutic target.

Nature Communications · Dec 16, 2021Peer-reviewedMolecular Biology

Whole Genome and Exome Sequencing Reference Datasets from A Multi-center and Cross-platform Benchmark Study

Yongmei Zhao, Li Tai Fang, Tsai-Wei Shen, Sulbha Choudhari, Keyur Talsania, Xiongfong Chen, Jyoti Shetty, Yuliya Kriga, Bao Quoc Tran, Bin Zhu, Zhong Chen, Wanqiu Chen, Charles Wang, Erich B. Jaeger, Daoud M. Meerzaman, , Wenming Xiao

The paper presents whole-genome and whole-exome sequencing datasets from a multi-center, cross-platform study to benchmark NGS technologies and bioinformatics pipelines in cancer genomics.

Scientific Data · Nov 9, 2021Peer-reviewedBioinformatics

Cross-Site Comparison of Ribosomal Depletion Kits for Illumina RNAseq Library Construction

Zachary T. Herbert, Jamie P. Kershner, Vincent L. Butty, Jyothi Thimmapuram, Sulbha Choudhari, Yuriy O. Alekseyev, Jun Fan, Jessica W. Podnar, Edward Wilcox, Jenny R. Gipson, Allison F. Gillaspy, Kristen Jepsen, Sandra Splinter BonDurant, Krystalynne Morris, Maura Berkeley, , Stuart S. Levine

The paper compares ribosomal depletion kits for RNAseq library construction, finding differences in ease of use and transcript length impact on library efficiency.

BMC Genomics · Mar 15, 2018Peer-reviewedGenomics