Characterisation of SpoT-disruption induced metabolic shift in bacteria
Zhi Ying Kho, Jinxin Zhao, Mei-Ling Han, Mohammad A. K. Azad, Christopher Barlow, Tony Velkov, Jian Li
This study investigates the metabolic changes in a spoT-disrupted Acinetobacter baumannii mutant under polymyxin treatment, revealing altered metabolite profiles linked to increased antibiotic susceptibility.
bioRxiv · Dec 6, 2025 · PreprintMicrobiology