Tony Velkov

This study identifies key residues in hPepT2 involved in polymyxin interaction, showing that modifying these residues reduces nephrotoxicity while maintaining antibacterial activity.

This study uses metabolomics to analyze how two CLOs disrupt MRSA membranes, revealing distinct metabolic changes that indicate membrane destabilization and lipid remodeling.

This study investigates the metabolic changes in a spoT-disrupted Acinetobacter baumannii mutant under polymyxin treatment, revealing altered metabolite profiles linked to increased antibiotic susceptibility.

This study uses single-cell RNA-seq to reveal concentration-dependent survival trajectories of Acinetobacter baumannii under antibiotic treatment, uncovering hidden heterogeneity and resistance mechanisms.

This study uses metabolomics to reveal that C12-o-(BG-D)-10 disrupts bacterial membrane organization and multiple metabolic pathways, contributing to its antimicrobial activity against MRSA.

The paper identifies sialylation changes in mouse sperm during capacitation, showing that sialylation of ACO2 inhibits its activity, potentially driving the metabolic switch from oxidative phosphorylation to glycolysis.