Author

Christopher J. Podracky

Broad Institute

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Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aditya RaguramiD· 1 shared Andrew T. Nelson· 1 shared Andrew V. AnzaloneiD· 1 shared David R. LiuiD· 1 shared Jaron A. M. MerceriD· 1 shared Jonathan Ma LevyiD· 1 shared Luke W. KoblaniD· 1 shared Xin D. GaoiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

Aditya RaguramORCID

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1 paper

Recent·Most cited

Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinases

Andrew V. Anzalone, Xin D. Gao, Christopher J. Podracky, Andrew T. Nelson, Luke W. Koblan, Aditya Raguram, Jonathan Ma Levy, Jaron A. M. Mercer, David R. Liu

This paper introduces twin prime editing (twinPE) and its combination with site-specific recombinases to enable precise DNA deletion, replacement, integration, and inversion in human cells without double-strand breaks.

bioRxiv · Nov 1, 2021 · PreprintGenomics