Author

Andrew V. Anzalone

Broad InstituteORCID 0000-0003-2531-5589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Assay:proteomics· 1 Research Focus:software / tool· 1 Organism:yeast· 1

Frequent Co-Authors

David R. LiuiD· 2 shared Aditya RaguramiD· 1 shared Andrew T. Nelson· 1 shared Christopher J. Podracky· 1 shared J. Keith JoungiD· 1 shared Jaron A. M. MerceriD· 1 shared Jonathan Ma LevyiD· 1 shared Jonathan Y. HsuiD· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

David R. LiuORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintNov 1, 2021

Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinases

Andrew V. Anzalone, Xin D. Gao, Christopher J. Podracky…·David R. Liu

This paper introduces twin prime editing (twinPE) and its combination with site-specific recombinases to enable precise DNA deletion, replacement, integration, and inversion in human cells without double-strand breaks.

16 citations

humanexperimental assay

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Synthetic BiologybioRxivPreprintApr 9, 2021

FRAME-tags: genetically encoded fluorescent markers for multiplexed barcoding and time-resolved tracking of live cells

Andrew V. Anzalone, Miguel Jiménez, Virginia W. Cornish

The paper introduces FRAME-tags, genetically encoded fluorescent barcodes that enable scalable and time-resolved tracking of live cells using unique FP expression ratios.

8 citations

yeastproteomics

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BioinformaticsNature CommunicationsPeer-reviewedFeb 15, 2021

PrimeDesign software for rapid and simplified design of prime editing guide RNAs

Jonathan Y. Hsu, Julian Grünewald, Regan N. Szalay…·Luca Pinello

PrimeDesign is a tool for designing prime editing guide RNAs, enabling single and combination edits, and it supports the creation of a database for over 68,500 pathogenic variants.

190 citationstop 1%

humanCRISPR screen

𝕏 PostBluesky