ShapeUpLMD: An Automated Pipeline for Spatially Optimized Laser Microdissection in Multi-omic Tissue Profiling
Joshua P. Schaaf, Dave Mitchell, Jonathan D. Ogata, Sakiyah TaQee, Katlin N. Wilson, Kelly A. Conrads, Jeremy Loffredo, Brian L. Hood, Tamara S. Abulez, Allison L. Hunt, Andrea Langeland, Paulette Y. Mhawech-Fauceglia, Kathleen M. Darcy, Christopher M. Tarney, George Larry Maxwell, , Nicholas W. Bateman
ShapeUpLMD automates ROI optimization for laser microdissection, improving tumor purity and spatial accuracy in multi-omic tissue profiling.
bioRxiv · Jan 27, 2026 · PreprintCancer Biology