Author
Henry M. Jackson FoundationORCID 0000-0001-5325-5064Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Brett Schroeder, Jae Choi, Alejandro A. Schäffer…·Anish Thomas
The paper identifies CLDN3 as a tumor-selective target in SCLC using proteogenomic analysis and validates its therapeutic potential with a monoclonal antibody.
Joshua P. Schaaf, Dave Mitchell, Jonathan D. Ogata…·Nicholas W. Bateman
ShapeUpLMD automates ROI optimization for laser microdissection, improving tumor purity and spatial accuracy in multi-omic tissue profiling.
Cara C. Schafer, Tamara S. Abulez, Xijun Zhang…·Shyh‐Han Tan
This study uses proteogenomics to identify ancestry-specific and shared molecular drivers in prostate cancer, revealing distinct biological programs and improving risk prediction.
Christopher M. Tarney, Paulette Y. Mhawech-Fauceglia, Jonathan D. Ogata…·Nicholas W. Bateman
The paper identifies conserved protein alterations and elevated MUC16 in low-grade serous ovarian cancers through quantitative proteomics and validation across multiple datasets.
Parth Anil Desai, Nobuyuki Takahashi, Rajesh Kumar…·Anish Thomas
This study maps the SCLC tumor microenvironment and identifies cancer-associated fibroblasts as key drivers of neuroendocrine state plasticity and poor prognosis.
Pang-ning Teng, Joshua P. Schaaf, Tamara S. Abulez…·Nicholas W. Bateman
ProteoMixture estimates cell type proportions in bulk tissue proteomics data using optimized protein signatures validated on high-grade serous ovarian cancer samples.