Non-canonical, potassium-driven cerebrospinal fluid clearance
Huixin Xu, Ryann M. Fame, Cameron Sadegh, Jason D. B. Sutin, Christopher Naranjo, Della Syau, Jin Cui, Frederick B. Shipley, Amanda N. Vernon, Fan Gao, Yong Zhang, Michael J. Holtzman, Myriam Heiman, Benjamin Curtis Warf, Pei‐Yi Lin, Maria K. Lehtinen
The paper identifies potassium-driven cerebrospinal fluid (CSF) clearance through the choroid plexus during a critical neurodevelopmental phase in mice, showing its role in preventing hydrocephalus.
Nature Communications · Jan 19, 2021Peer-reviewedNeuroscience