Huixin Xu

This study creates a multi-modal atlas of choroid plexus pathology across aging and Alzheimer's disease, identifying fibrosis, calcification, and macrophage abnormalities as key features.

This study identifies intraventricular macrophages (IVMs) as first responders to blood in developing brains, showing their dynamic behavior and unique transcriptional profiles.

This study generates Sspo knockout mice and finds reduced brain ventricle size but only minor spine curvature defects.

The paper shows the ChP acts as an immune organ in brain inflammation, with immune cell interactions and epithelial cell specialization regulating the barrier.

The paper identifies potassium-driven cerebrospinal fluid (CSF) clearance through the choroid plexus during a critical neurodevelopmental phase in mice, showing its role in preventing hydrocephalus.

This study demonstrates the feasibility of whole genome sequencing of fetal genomes from amniotic fluid, revealing additional genetic and clinical information beyond chromosomal abnormalities.