Structure and function of IWS1 in transcription elongation
Della Syau, Felix Steinruecke, Sophie Roth, Ernst Schmid, Karen Adelman, Johannes C. Walter, Lucas Farnung
This study identifies IWS1 as a modular scaffold that organizes the transcription elongation complex through its disordered region, revealing its role in recruitment and stimulation of elongation.
Nucleic Acids Research · Apr 9, 2026Peer-reviewedMolecular Biology