Author

Christopher Ne Ville

University of Southern California

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:CRISPR screen· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Ian M. EhrenreichiD· 2 shared Alessandro Luis Venega CoradiniiD· 1 shared Cara B. HulliD· 1 shared Charley Wang· 1 shared Daniel T. LuskiD· 1 shared Darach MilleriD· 1 shared Ilan GoldsteiniD· 1 shared Joseph J. HaleiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenetics

Ian M. EhrenreichORCID

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2 papers

Recent·Most cited

Genome-scale analysis of interactions between genetic perturbations and natural variation

Joseph J. Hale, Takeshi Matsui, Ilan Goldstein, Martin N. Mullis, Kevin R. Roy, Christopher Ne Ville, Darach Miller, Charley Wang, Trevor W. Reynolds, Lars Michael Steinmetz, Sasha F. Levy, Ian M. Ehrenreich

The paper identifies gene-perturbation interactions across genetic backgrounds in yeast using CRISPRi and combinatorial DNA barcode sequencing, revealing 460 genes with variable effects and 234 interacting loci.

Nature Communications · May 18, 2024Peer-reviewedGenetics

Building synthetic chromosomes from natural DNA

Alessandro Luis Venega Coradini, Christopher Ne Ville, Zachary Krieger, Joshua Roemer, Cara B. Hull, Shawn Yang, Daniel T. Lusk, Ian M. Ehrenreich

This paper introduces CReATiNG, a method to build synthetic chromosomes from natural DNA in yeast, enabling chromosome recombination, modification, and deletion of non-adjacent regions.

Nature Communications · Dec 20, 2023Peer-reviewedSynthetic Biology