Pathogenic MAPK8IP3 variants drive distinct motor and behavioral phenotypes in humans and mice
Camerron M. Crowder, Lyndsay R. Watkins, Alexa Geltzeiler, Priya Patel, Judit Perez Ortiz, Danielle Schmidt, Christopher Schmitz, Jalen Aguilar, Shraddha Ghanta, Wendy K. Chung, Swetha Gowrishankar, Laura Lambert
The paper compares clinical and behavioral effects of different MAPK8IP3 variants in humans and mice, showing shared and distinct phenotypes linked to specific protein domains.
bioRxiv · Jul 24, 2026 · PreprintNeuroscience