Camerron M. Crowder

Pathogenic MAPK8IP3 variants drive distinct motor and behavioral phenotypes in humans and mice

The paper compares clinical and behavioral effects of different MAPK8IP3 variants in humans and mice, showing shared and distinct phenotypes linked to specific protein domains.

Anti-Parkinsonian Drugs Rescue Locomotor Deficits in JIP3 Knockout Zebrafish: Implications for Treating Patients with MAPK8IP3-related Neurodevelopmental Disorders

The paper identifies amantadine and levodopa as potential therapies for JIP3-related neurodevelopmental disorders using zebrafish models and AI-assisted drug screening.

Small molecule modulator of neuronal lysosome positioning and function resolves Alzheimers Disease-linked pathologies in cultured human neurons

A small molecule modulates neuronal lysosome positioning and function, reducing amyloid-beta levels and rescuing pathologies in human neurons and zebrafish.

G protein-coupled estrogen receptor is not required for sex determination or ovary function in zebrafish

This study shows that GPER is not required for sex determination, ovary development, or fertility in zebrafish.

Nuclear androgen receptor regulates testes organization and oocyte maturation in zebrafish

This study shows that zebrafish AR is essential for testis organization and oocyte maturation but not for male sexual differentiation.