Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis
Adrien Grimont, David J. Falvo, Whitney J. Sisso, Francisco dos Santos, Christopher W. Chan, Paul Zumbo, William B. Fall, Katherine R. Ferrick, Grace Pan, Megan Cleveland, Tomer M. Yaron, Alexa Osterhoudt, Yinuo Meng, María Paz Zafra, André F. Rendeiro, , Rohit Chandwani
This study investigates how different KRAS mutations drive distinct phenotypic outcomes in pancreatic tumorigenesis, revealing mutation-specific oncogenic pathways and therapeutic implications.
Developmental Cell · Jul 21, 2026Peer-reviewedCancer Biology