Author

Francisco dos Santos

University of AveiroORCID 0000-0002-2046-2742Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Adrien GrimontiD· 1 shared Alexa OsterhoudtiD· 1 shared André F. RendeiroiD· 1 shared Anil K. Rustgi· 1 shared Bárbara Bola· 1 shared Bruno Bernardes de JesusiD· 1 shared Christian BäriD· 1 shared Christopher W. Chan· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Adrien GrimontORCID

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2 papers

Recent·Most cited

Cancer BiologyDevelopmental CellPeer-reviewedJul 21, 2026

Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis

Adrien Grimont, David J. Falvo, Whitney J. Sisso…·Rohit Chandwani

This study investigates how different KRAS mutations drive distinct phenotypic outcomes in pancreatic tumorigenesis, revealing mutation-specific oncogenic pathways and therapeutic implications.

3 citationstop 3%

mouseexperimental assay

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Cell BiologyAging CellPeer-reviewedNov 14, 2024

Metabolic and age-associated epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes

Francisco dos Santos, Magda Correia, Rafaela Dias…·Sandrina Nóbrega Pereira

This study identifies metabolic and age-related epigenetic barriers in converting mouse fibroblasts to induced cardiomyocytes, showing that metabolic modulation enhances reprogramming efficiency.

9 citations

mousemetabolomics

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