Developmental BiologybioRxivPreprint
An organoid CRISPRi screen revealed that SOX9 primes human fetal lung tip progenitors to receive WNT and RTK signals
Dawei Sun, Oriol Llorà-Batlle, Jelle van den Ameele…·Emma L. Rawlins
The paper uses a CRISPRi screen in human fetal lung organoids to identify SOX9 as a key regulator of progenitor self-renewal, showing it primes cells to receive WNT and RTK signals.
5 citations