Jiulin Du

NeuroPack compresses 3D neuroimaging data with high fidelity and ultra-high compression ratios using a hyperprior-driven deep learning toolkit.

This paper develops an efficient method for retrograde monosynaptic tracing in larval zebrafish neural circuits using modified rabies viruses.

This paper introduces a Dual-NIR Switch using near-infrared light to control neuronal activity in mice without sustained illumination, enabling on-demand neuromodulation.

The paper identifies a neuron-glia circuit in zebrafish that anticipates hypoxia by integrating behavioral intent and physiological state to prevent internal oxygen depletion.

iBrAVE integrates multimodal and multiscale brain atlas data across species, enabling interactive analysis of molecular, structural, and functional information.

This study shows that directional myelin growth in zebrafish is driven by a Wnt4b gradient and is essential for proper axon function and behavior.

The paper maps synaptic input architecture of LC-NE neurons in larval zebrafish, revealing broad-yet-sparse input organization across brain regions.

The paper reveals how locus coeruleus-norepinephrine neurons organize to regulate brain-wide neural dynamics through region-specific axon projections and synchronized firing.

The paper builds a biologically constrained spiking neural network of the zebrafish optic tectum to reveal how serotonergic systems and interneuron-type mechanisms enable adaptive visuomotor transformation.

The paper creates a comprehensive atlas of larval zebrafish neuron morphology, including excitatory and inhibitory identities and connectivity patterns.

The paper develops a super-resolution microscopy technique to image neuronal morphology in behaving animals, revealing fast spinule dynamics and PSD-95 cluster correlations.

This study uses GRIT to measure tryptophan dynamics across species and scales, revealing links between tryptophan metabolism, inflammation, and behavior.

This study shows blood flow promotes brain pericyte proliferation via Piezo1 in zebrafish, highlighting a new role for hemodynamics in vascular development.

The paper develops an ultrasensitive GRABATP1.0 sensor to detect extracellular ATP in real time, demonstrating its use in vitro and in vivo across multiple conditions.

This paper introduces an efficient method for genomic DNA replacement in zebrafish using NHEJ-mediated repair at non-coding regions, showing higher efficiency than HR/HDR.

The paper introduces confocal light field microscopy to capture fast volumetric dynamics in thick brain tissue, demonstrating its use in recording calcium transients and blood cell movement in zebrafish and mice.

This paper describes a CRISPR/Cas9-based method to generate zebrafish with a conditional knockout-knockin switch that can be visualized using fluorescent reporters.

The paper develops GRABNE sensors for rapid, specific in vivo detection of norepinephrine, demonstrating their use in various experimental contexts.

This paper develops GRABDA sensors to measure dopamine with high precision in multiple organisms during complex behaviors.

This study develops a technique to image whole brain neural activity in freely behaving larval zebrafish during specific behaviors.