Inversion of a topological domain leads to restricted changes in its gene expression and affects inter-domain communication
Rafael Galupa, Christel Picard, Nicolas Servant, Elphège Pierre Nora, Yinxiu Zhan, Joke Gerarda van Bemmel, Fatima El Marjou, Colin Johanneau, Maud Borensztein, Katia Ancelin, Luca Giorgetti, Édith Heard
The paper inverts a topological domain and shows it causes limited gene expression changes but affects inter-domain communication, particularly in Xist expression.
Development · May 1, 2022Peer-reviewedGenomics