Complement therapeutic Factor H-IgG proteins as pre-exposure prophylaxes against Lyme borreliae infections
Connor W. McKaig, Jill Malfetano, Thi Hai Yen Tran, Xiuli Yang, Utpal Pal, Keith L. Wycoff, Yi‐Pin Lin
This paper demonstrates that FH-Fc constructs can kill Lyme borreliae and reduce infection in vivo by targeting complement evasion mechanisms.
The Journal of Immunology · Aug 22, 2025Peer-reviewedMicrobiology