Author

Keith L. Wycoff

Planet Biotechnology (United States)ORCID 0000-0002-5343-5329Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:protein structure· 1

Frequent Co-Authors

Alison K. CrissiD· 1 shared Bo Zheng· 1 shared Connor W. McKaig· 1 shared Gretchen Telford· 1 shared Jill Malfetano· 1 shared Jintang Du· 1 shared Jutamas ShaughnessyiD· 1 shared Kevin J. WhaleyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alison K. CrissORCID

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2 papers

Recent·Most cited

ImmunologyPLoS ONEPeer-reviewedAug 25, 2026

Pre-clinical efficacy of a C4BP hexameric IgG Fc fusion protein against Neisseria gonorrhoeae

Jutamas Shaughnessy, Jintang Du, Mary W. Broden…·Sanjay Ram

This paper demonstrates that a hexameric C4BP IgG Fc fusion protein significantly enhances complement-dependent bactericidal activity and reduces gonococcal vaginal colonization in mice.

DOI 10.1371/journal.pone.0350782

mouseexperimental assay

𝕏 PostBluesky

MicrobiologyThe Journal of ImmunologyPeer-reviewedAug 22, 2025

Complement therapeutic Factor H-IgG proteins as pre-exposure prophylaxes against Lyme borreliae infections

Connor W. McKaig, Jill Malfetano, Thi Hai Yen Tran…·Yi‐Pin Lin

This paper demonstrates that FH-Fc constructs can kill Lyme borreliae and reduce infection in vivo by targeting complement evasion mechanisms.

1 citation

mouseprotein structure

𝕏 PostBluesky